{"product_id":"nad-buffered-750mg-peptide","title":"NAD+ Buffered","description":"\u003cdiv class=\"product-description\"\u003e\n\n\u003ch1\u003eNAD+ Kit\u003c\/h1\u003e\n\n\u003ch3\u003eHigh-Purity Nicotinamide Adenine Dinucleotide (NAD+)\u003c\/h3\u003e\n\n\u003cp\u003e\nNAD+ (Nicotinamide Adenine Dinucleotide) is a naturally occurring coenzyme found in all living cells and plays a critical role in cellular energy production, mitochondrial function, DNA repair, and metabolic regulation. NAD+ research has become increasingly important in studies related to aging biology, cellular metabolism, and regenerative science.\n\u003c\/p\u003e\n\n\u003chr\u003e\n\n\u003ch2\u003eProduct Specifications\u003c\/h2\u003e\n\n\u003ctable border=\"1\" cellpadding=\"10\" cellspacing=\"0\" width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003eParameter\u003c\/th\u003e\n\u003cth\u003eResult\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCost per milligram\u003c\/td\u003e\n\u003ctd\u003e$0.10 – $0.15\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePurity\u003c\/td\u003e\n\u003ctd\u003e99.92%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCertified Endotoxin-safe\u003c\/td\u003e\n\u003ctd\u003eYes\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eIndependently Tested\u003c\/td\u003e\n\u003ctd\u003eYes\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eManufacturer ID\u003c\/td\u003e\n\u003ctd\u003eVI32\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBatch ID\u003c\/td\u003e\n\u003ctd\u003eNDB202601\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\n\u003chr\u003e\n\n\u003ch2\u003eQuality Assurance\u003c\/h2\u003e\n\n\u003cul\u003e\n\u003cli\u003e✓ Independently Tested\u003c\/li\u003e\n\u003cli\u003e✓ High-Purity Research Grade Material\u003c\/li\u003e\n\u003cli\u003e✓ Endotoxin Certified Safe\u003c\/li\u003e\n\u003cli\u003e✓ Manufactured Under Strict Quality Standards\u003c\/li\u003e\n\u003cli\u003e✓ Batch-Specific Analytical Verification\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003chr\u003e\n\n\u003ch2\u003eResearch Studies\u003c\/h2\u003e\n\n\u003cp\u003e\u003cem\u003eFor Educational Purposes Only\u003c\/em\u003e\u003c\/p\u003e\n\n\u003ch3\u003eStudy 1: Dihydronicotinamide Riboside is a Potent NAD+ Concentration Enhancer In Vitro and In Vivo\u003c\/h3\u003e\n\n\u003cp\u003e\n\u003cstrong\u003eAuthors:\u003c\/strong\u003e Yue Yang, Farheen Sultana Mohammed, Ning Zhang, Anthony A. Sauve\n\u003c\/p\u003e\n\n\u003cp\u003e\n\u003cstrong\u003eSource:\u003c\/strong\u003e\n\u003ca href=\"https:\/\/www.jbc.org\/article\/S0021-9258(20)35173-5\/fulltext\" target=\"_blank\"\u003e\nhttps:\/\/www.jbc.org\/article\/S0021-9258(20)35173-5\/fulltext\n\u003c\/a\u003e\n\u003c\/p\u003e\n\n\u003ch4\u003eScientific Findings\u003c\/h4\u003e\n\n\u003cp\u003e\nResearchers evaluated dihydronicotinamide riboside (NRH), a novel NAD+ precursor, in multiple mammalian cell models. Results demonstrated that NRH rapidly increased intracellular NAD+ concentrations by approximately 2.5 to 10 times within one hour of administration.\n\u003c\/p\u003e\n\n\u003cp\u003e\nCompared with traditional NAD+ precursors such as nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN), NRH consistently produced greater NAD+ elevation at equivalent concentrations. Increased NAD+ availability also improved cellular redox balance and enhanced resistance to oxidative and genotoxic stress.\n\u003c\/p\u003e\n\n\u003cp\u003e\nThe study further identified a previously uncharacterized pathway involved in NRH metabolism, suggesting alternative mechanisms for cellular NAD+ biosynthesis.\n\u003c\/p\u003e\n\n\u003ch4\u003ePlain English Interpretation\u003c\/h4\u003e\n\n\u003cp\u003e\nThis study showed that increasing NAD+ levels inside cells can significantly improve cellular energy production and stress resistance. Researchers found that NRH, a specialized NAD+ precursor, was particularly effective at boosting NAD+ levels compared with existing alternatives.\n\u003c\/p\u003e\n\n\u003cp\u003e\nHigher NAD+ levels helped cells maintain healthier energy balance and improved their ability to withstand damage caused by oxidative stress.\n\u003c\/p\u003e\n\n\u003chr\u003e\n\n\u003ch3\u003eStudy 2: NAD+\/NADH Redox Alterations Reconfigure Metabolism and Rejuvenate Senescent Human Mesenchymal Stem Cells In Vitro\u003c\/h3\u003e\n\n\u003cp\u003e\n\u003cstrong\u003eAuthors:\u003c\/strong\u003e Xuegang Yuan, Yijun Liu, Brent M. Bijonowski, Ang-Chen Tsai, Qin Fu, Timothy M. Logan, Teng Ma, Yan Li\n\u003c\/p\u003e\n\n\u003cp\u003e\n\u003cstrong\u003eSource:\u003c\/strong\u003e\n\u003ca href=\"https:\/\/www.nature.com\/articles\/s42003-020-01514-y\" target=\"_blank\"\u003e\nhttps:\/\/www.nature.com\/articles\/s42003-020-01514-y\n\u003c\/a\u003e\n\u003c\/p\u003e\n\n\u003ch4\u003eScientific Findings\u003c\/h4\u003e\n\n\u003cp\u003e\nThis study examined how NAD+ influences cellular aging in human mesenchymal stem cells.\n\u003c\/p\u003e\n\n\u003cp\u003e\nResearchers observed that aging stem cells displayed lower NAD+\/NADH ratios, reduced mitochondrial function, and diminished activity of Sirtuin-1 (SIRT1), a key regulator of cellular metabolism.\n\u003c\/p\u003e\n\n\u003cp\u003e\nRestoration of intracellular NAD+ levels successfully improved mitochondrial performance, enhanced cellular metabolism, increased SIRT1 activity, and partially reversed several markers associated with cellular senescence.\n\u003c\/p\u003e\n\n\u003ch4\u003ePlain English Interpretation\u003c\/h4\u003e\n\n\u003cp\u003e\nScientists found that declining NAD+ levels appear to be closely linked with cellular aging.\n\u003c\/p\u003e\n\n\u003cp\u003e\nWhen NAD+ levels were restored, older stem cells began functioning more like younger cells. Energy production improved, mitochondrial activity increased, and several biological signs of aging became less pronounced.\n\u003c\/p\u003e\n\n\u003cp\u003e\nThese findings highlight the important role NAD+ plays in maintaining healthy cellular function.\n\u003c\/p\u003e\n\n\u003chr\u003e\n\n\u003ch3\u003eStudy 3: Cellular NAD Replenishment Confers Marked Neuroprotection Against Ischemic Cell Death\u003c\/h3\u003e\n\n\u003cp\u003e\n\u003cstrong\u003eAuthors:\u003c\/strong\u003e Suping Wang, Zili Xing, Peter S. Vosler, Hannah Yin, et al.\n\u003c\/p\u003e\n\n\u003cp\u003e\n\u003cstrong\u003eSource:\u003c\/strong\u003e\n\u003ca href=\"https:\/\/www.ahajournals.org\/doi\/10.1161\/strokeaha.107.509158\" target=\"_blank\"\u003e\nhttps:\/\/www.ahajournals.org\/doi\/10.1161\/strokeaha.107.509158\n\u003c\/a\u003e\n\u003c\/p\u003e\n\n\u003ch4\u003eScientific Findings\u003c\/h4\u003e\n\n\u003cp\u003e\nResearchers investigated whether direct NAD+ supplementation could protect neurons exposed to oxygen-glucose deprivation, an established laboratory model of ischemic injury.\n\u003c\/p\u003e\n\n\u003cp\u003e\nNAD+ administration significantly reduced neuronal cell death and improved survival following injury. The protective effects were associated with enhanced DNA repair activity and restoration of the base excision repair (BER) pathway.\n\u003c\/p\u003e\n\n\u003cp\u003e\nNAD+ supplementation also reduced oxidative DNA damage and improved the function of key DNA repair enzymes involved in cellular recovery.\n\u003c\/p\u003e\n\n\u003ch4\u003ePlain English Interpretation\u003c\/h4\u003e\n\n\u003cp\u003e\nThis study demonstrated that NAD+ can help brain cells recover from severe metabolic stress in laboratory conditions.\n\u003c\/p\u003e\n\n\u003cp\u003e\nResearchers found that increasing NAD+ availability improved the cells' ability to repair damaged DNA and significantly reduced cell death. These findings suggest that NAD+ plays an important role in supporting cellular resilience and maintaining genomic stability.\n\u003c\/p\u003e\n\n\u003chr\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\n\n\u003cul\u003e\n\u003cli\u003eCellular Energy Metabolism Research\u003c\/li\u003e\n\u003cli\u003eMitochondrial Function Studies\u003c\/li\u003e\n\u003cli\u003eDNA Repair Pathway Research\u003c\/li\u003e\n\u003cli\u003eCellular Aging Mechanisms\u003c\/li\u003e\n\u003cli\u003eStem Cell Biology Research\u003c\/li\u003e\n\u003cli\u003eNeuroprotection Studies\u003c\/li\u003e\n\u003cli\u003eOxidative Stress Investigations\u003c\/li\u003e\n\u003cli\u003eMetabolic Health Research\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003chr\u003e\n\n\u003ch2\u003eDisclaimer\u003c\/h2\u003e\n\n\u003cp\u003e\n\u003cstrong\u003eAll products are intended strictly for laboratory research and in-vitro experimentation purposes only.\u003c\/strong\u003e\n\u003c\/p\u003e\n\n\u003cp\u003e\n\u003cstrong\u003eNot for human consumption.\u003c\/strong\u003e\n\u003c\/p\u003e\n\n\u003cp\u003e\n\u003cstrong\u003eNot for therapeutic, diagnostic, veterinary, or clinical use.\u003c\/strong\u003e\n\u003c\/p\u003e\n\n\u003cp\u003e\n\u003cstrong\u003eThis product has not been evaluated by the U.S. Food and Drug Administration (FDA).\u003c\/strong\u003e\n\u003c\/p\u003e\n\n\u003cp\u003e\n\u003cstrong\u003eFor qualified research professionals only.\u003c\/strong\u003e\n\u003c\/p\u003e\n\n\u003c\/div\u003e","brand":"My Store 3","offers":[{"title":"Default Title","offer_id":47911681294554,"sku":null,"price":45.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0824\/4615\/5994\/files\/JPMolecularLabsNAD_1500mgboxandinjectionvial.png?v=1779600370","url":"https:\/\/zzpeptide.com\/products\/nad-buffered-750mg-peptide","provider":"JP MOLECULAR LABS","version":"1.0","type":"link"}