{"product_id":"tb-500-10mg-peptide","title":"TB-500(TB4)","description":"\u003csection class=\"research-product-section\"\u003e\n\u003cdiv class=\"product-header\"\u003e\n\u003ch1\u003eTB-500 (TB4) Kit\u003c\/h1\u003e\n\u003cp class=\"product-subtitle\"\u003eResearch-Grade Thymosin Beta-4 Peptide Kit\u003cstrong\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"product-specifications\"\u003e\n\u003ch2\u003eProduct Specifications\u003c\/h2\u003e\n\u003ctable\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eCost Per Milligram\u003c\/td\u003e\n\u003ctd\u003e$4.90 – $6.50\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePurity\u003c\/td\u003e\n\u003ctd\u003e99.86%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCertified Endotoxin-Safe\u003c\/td\u003e\n\u003ctd\u003eYes\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eIndependently Tested\u003c\/td\u003e\n\u003ctd\u003eYes\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eManufacturer ID\u003c\/td\u003e\n\u003ctd\u003eWF03\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBatch ID\u003c\/td\u003e\n\u003ctd\u003eTB202601\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"seo-content\"\u003e\n\u003ch2\u003eTB-500 (TB4) Research Peptide Overview\u003c\/h2\u003e\n\u003cp\u003eTB-500, also known as Thymosin Beta-4 (TB4), is a synthetic peptide widely utilized in scientific research involving cellular migration, tissue regeneration, angiogenesis, and wound-healing pathways. Researchers study TB-500 for its potential role in supporting cell movement, cytoskeletal organization, and tissue remodeling processes in controlled laboratory settings.\u003c\/p\u003e\n\u003cp\u003eThis research-grade TB-500 kit is manufactured under strict quality standards and undergoes independent analytical verification for purity and endotoxin safety. Each batch is screened to ensure consistency for in-vitro laboratory applications.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"research-studies\"\u003e\n\u003ch2\u003eResearch Studies\u003c\/h2\u003e\n\u003cp\u003e\u003cem\u003eFor educational and scientific purposes only.\u003c\/em\u003e\u003c\/p\u003e\n\u003carticle class=\"study-item\"\u003e\n\u003ch3\u003eStudy 1: Simultaneous Quantification of TB-500 and Its Metabolites in In-Vitro Experiments and Rats by UHPLC-Q-Exactive Orbitrap MS\/MS\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAuthors:\u003c\/strong\u003e Khandoker Asiqur Rahaman, Anca Raluca Muresan, Hophil Min, Junghyun Son, Hyung-Seop Han, Min-Jung Kang, Oh-Seung Kwon\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSource:\u003c\/strong\u003e ScienceDirect\u003c\/p\u003e\n\u003ch4\u003eScientific Findings\u003c\/h4\u003e\n\u003cp\u003eResearchers developed and validated an advanced analytical method capable of simultaneously measuring TB-500 and its metabolites using UHPLC-Q-Exactive Orbitrap mass spectrometry. Metabolic profiling was conducted in human serum, enzymatic systems, and rat urine samples.\u003c\/p\u003e\n\u003cp\u003eThe investigation identified Ac-LK as the primary metabolite and Ac-LKK as a long-term metabolite. Biological activity testing in fibroblast-based wound-healing assays demonstrated that the metabolite Ac-LKKTE exhibited significant wound-healing activity, while neither TB-500 nor its metabolites displayed measurable cytotoxicity.\u003c\/p\u003e\n\u003ch4\u003ePlain English Interpretation\u003c\/h4\u003e\n\u003cp\u003eScientists studied how TB-500 breaks down after exposure to biological systems. They discovered that one specific breakdown product may be responsible for many of the regenerative effects commonly associated with TB-500. The findings suggest that certain metabolites generated from TB-500 may play a more important role than the original peptide itself in supporting cellular repair processes.\u003c\/p\u003e\n\u003c\/article\u003e\n\u003carticle class=\"study-item\"\u003e\n\u003ch3\u003eStudy 2: Investigation of In Vitro\/Ex Vivo TB-500 Metabolism, Synthesis of Relevant Metabolites and Detection Limits in Urine and Plasma\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAuthors:\u003c\/strong\u003e P. Van Eenoo\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSource:\u003c\/strong\u003e World Anti-Doping Agency (WADA)\u003c\/p\u003e\n\u003ch4\u003eScientific Findings\u003c\/h4\u003e\n\u003cp\u003eThis research characterized the metabolic behavior of TB-500 using human liver microsomes, S9 fractions, plasma, and serum models. Investigators found that TB-500 undergoes progressive C-terminal cleavage while maintaining protection through N-terminal acetylation.\u003c\/p\u003e\n\u003cp\u003eThree primary metabolites were synthesized and characterized, enabling development of highly sensitive analytical detection methods capable of identifying TB-500-related compounds at picogram-per-milliliter concentrations.\u003c\/p\u003e\n\u003ch4\u003ePlain English Interpretation\u003c\/h4\u003e\n\u003cp\u003eResearchers mapped the exact way TB-500 is broken down in biological environments. By identifying specific metabolites, they were able to create highly sensitive testing methods. This work provides valuable insight into the stability and metabolic profile of TB-500 and improves scientific understanding of how the peptide behaves after administration.\u003c\/p\u003e\n\u003c\/article\u003e\n\u003carticle class=\"study-item\"\u003e\n\u003ch3\u003eStudy 3: Utilizing Developmentally Essential Secreted Peptides Such as Thymosin Beta-4 to Remind the Adult Organs of Their Embryonic State\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAuthors:\u003c\/strong\u003e Klaudia Maar, Roland Hetenyi, Szabolcs Maar, Gabor Faskerti, Daniel Hanna, Balint Lippai, Aniko Takatsy, Ildiko Bock-Marquette\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSource:\u003c\/strong\u003e National Center for Biotechnology Information (NCBI)\u003c\/p\u003e\n\u003ch4\u003eScientific Findings\u003c\/h4\u003e\n\u003cp\u003eThis review examined the regenerative properties of Thymosin Beta-4 and summarized evidence demonstrating its involvement in cell migration, survival signaling, tissue remodeling, and cardiovascular regeneration.\u003c\/p\u003e\n\u003cp\u003eExperimental findings highlighted activation of Integrin-Linked Kinase (ILK) and downstream Akt signaling pathways, mechanisms associated with enhanced cellular survival and regenerative activity. The review discussed TB4’s potential role in supporting cardiac repair and tissue regeneration.\u003c\/p\u003e\n\u003ch4\u003ePlain English Interpretation\u003c\/h4\u003e\n\u003cp\u003eScientists reviewed a growing body of research showing that Thymosin Beta-4 may help cells activate natural repair mechanisms. By supporting cellular movement and survival pathways, TB4 appears to assist tissues in responding to injury and maintaining regenerative capacity. These findings have made TB4 an important subject of ongoing regenerative medicine research.\u003c\/p\u003e\n\u003c\/article\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"research-disclaimer\"\u003e\n\u003ch2\u003eResearch Use Disclaimer\u003c\/h2\u003e\n\u003cp\u003eAll products are supplied exclusively for laboratory research, analytical testing, and educational purposes. Products are intended for in-vitro research use only and are not approved for human consumption, veterinary use, diagnosis, treatment, cure, or prevention of any disease.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/section\u003e","brand":"My Store 3","offers":[{"title":"Default Title","offer_id":47911688995034,"sku":null,"price":65.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0824\/4615\/5994\/files\/JPMolecularLabsTB-500ThymosinBeta4peptidevialandbox.png?v=1779601442","url":"https:\/\/zzpeptide.com\/products\/tb-500-10mg-peptide","provider":"JP MOLECULAR LABS","version":"1.0","type":"link"}