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TB-500.
  • TB-500.
  • TB-500.
TB-500(TB4)

TB-500(TB4)

$65.00 USD
$65.00 USD

Purity:≥99%COA:✓ Available

Thymosin Beta-4 fragment peptide for wound healing and repair studies.

Features & Storage

  • Purity: ≥99%
  • Specification: 5mg/vial
  • Storage: Store at 2-8°C
  • COA: Available
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TB-500 (TB4) Kit

Research-Grade Thymosin Beta-4 Peptide Kit

Product Specifications

Cost Per Milligram $4.90 – $6.50
Purity 99.86%
Certified Endotoxin-Safe Yes
Independently Tested Yes
Manufacturer ID WF03
Batch ID TB202601

TB-500 (TB4) Research Peptide Overview

TB-500, also known as Thymosin Beta-4 (TB4), is a synthetic peptide widely utilized in scientific research involving cellular migration, tissue regeneration, angiogenesis, and wound-healing pathways. Researchers study TB-500 for its potential role in supporting cell movement, cytoskeletal organization, and tissue remodeling processes in controlled laboratory settings.

This research-grade TB-500 kit is manufactured under strict quality standards and undergoes independent analytical verification for purity and endotoxin safety. Each batch is screened to ensure consistency for in-vitro laboratory applications.

Research Studies

For educational and scientific purposes only.

Study 1: Simultaneous Quantification of TB-500 and Its Metabolites in In-Vitro Experiments and Rats by UHPLC-Q-Exactive Orbitrap MS/MS

Authors: Khandoker Asiqur Rahaman, Anca Raluca Muresan, Hophil Min, Junghyun Son, Hyung-Seop Han, Min-Jung Kang, Oh-Seung Kwon

Source: ScienceDirect

Scientific Findings

Researchers developed and validated an advanced analytical method capable of simultaneously measuring TB-500 and its metabolites using UHPLC-Q-Exactive Orbitrap mass spectrometry. Metabolic profiling was conducted in human serum, enzymatic systems, and rat urine samples.

The investigation identified Ac-LK as the primary metabolite and Ac-LKK as a long-term metabolite. Biological activity testing in fibroblast-based wound-healing assays demonstrated that the metabolite Ac-LKKTE exhibited significant wound-healing activity, while neither TB-500 nor its metabolites displayed measurable cytotoxicity.

Plain English Interpretation

Scientists studied how TB-500 breaks down after exposure to biological systems. They discovered that one specific breakdown product may be responsible for many of the regenerative effects commonly associated with TB-500. The findings suggest that certain metabolites generated from TB-500 may play a more important role than the original peptide itself in supporting cellular repair processes.

Study 2: Investigation of In Vitro/Ex Vivo TB-500 Metabolism, Synthesis of Relevant Metabolites and Detection Limits in Urine and Plasma

Authors: P. Van Eenoo

Source: World Anti-Doping Agency (WADA)

Scientific Findings

This research characterized the metabolic behavior of TB-500 using human liver microsomes, S9 fractions, plasma, and serum models. Investigators found that TB-500 undergoes progressive C-terminal cleavage while maintaining protection through N-terminal acetylation.

Three primary metabolites were synthesized and characterized, enabling development of highly sensitive analytical detection methods capable of identifying TB-500-related compounds at picogram-per-milliliter concentrations.

Plain English Interpretation

Researchers mapped the exact way TB-500 is broken down in biological environments. By identifying specific metabolites, they were able to create highly sensitive testing methods. This work provides valuable insight into the stability and metabolic profile of TB-500 and improves scientific understanding of how the peptide behaves after administration.

Study 3: Utilizing Developmentally Essential Secreted Peptides Such as Thymosin Beta-4 to Remind the Adult Organs of Their Embryonic State

Authors: Klaudia Maar, Roland Hetenyi, Szabolcs Maar, Gabor Faskerti, Daniel Hanna, Balint Lippai, Aniko Takatsy, Ildiko Bock-Marquette

Source: National Center for Biotechnology Information (NCBI)

Scientific Findings

This review examined the regenerative properties of Thymosin Beta-4 and summarized evidence demonstrating its involvement in cell migration, survival signaling, tissue remodeling, and cardiovascular regeneration.

Experimental findings highlighted activation of Integrin-Linked Kinase (ILK) and downstream Akt signaling pathways, mechanisms associated with enhanced cellular survival and regenerative activity. The review discussed TB4’s potential role in supporting cardiac repair and tissue regeneration.

Plain English Interpretation

Scientists reviewed a growing body of research showing that Thymosin Beta-4 may help cells activate natural repair mechanisms. By supporting cellular movement and survival pathways, TB4 appears to assist tissues in responding to injury and maintaining regenerative capacity. These findings have made TB4 an important subject of ongoing regenerative medicine research.

Research Use Disclaimer

All products are supplied exclusively for laboratory research, analytical testing, and educational purposes. Products are intended for in-vitro research use only and are not approved for human consumption, veterinary use, diagnosis, treatment, cure, or prevention of any disease.

Why Choose JP MOLECULAR LABS?

1. High Purity Standards

Manufactured in GMP-compliant facilities with purity levels exceeding 99%, verified through HPLC and Mass Spectrometry testing.

2. Comprehensive Quality Control

Every production batch undergoes strict quality inspections from raw materials to finished products, ensuring consistency and reliability.

3. Certificate of Analysis (COA) Available

Each batch is supplied with a detailed Certificate of Analysis, including purity, molecular weight, and analytical testing data.

4. Custom Manufacturing Capability

We provide custom peptide synthesis services tailored to your required sequence, purity level, quantity, and packaging specifications

5. Flexible Bulk Supply

From small research quantities to large-scale commercial production, ZZPeptide supports flexible order volumes with competitive pricing.

6. Fast Global Delivery

Reliable logistics solutions ensure timely delivery to customers worldwide, including North America, Europe, Australia, South America, and Asia.

7. Experienced Technical Support

With over 17 years of peptide manufacturing experience, our team provides professional technical consultation and product support.

8. Full Traceability

Every batch is fully traceable through our production and quality management systems, ensuring transparency and compliance.



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