GLP-1 Explained: How It Works for Weight Loss and Metabolism
GLP-1 (Glucagon-Like Peptide-1) is a natural hormone that plays a key role in regulating appetite, blood sugar, and digestion.
What is GLP-1?
GLP-1 is produced in the intestine after eating food. It signals the body to release insulin and reduce hunger.
How GLP-1 Works in the Body
- Stimulates insulin secretion
- Reduces glucagon levels
- Slows gastric emptying
- Signals fullness to the brain
GLP-1 and Weight Loss
GLP-1 reduces appetite by acting on the brain’s hunger center, leading to lower calorie intake and fat loss over time.
GLP-1-Based Drugs
- Semaglutide
- Tirzepatide
- Retatrutide (triple agonist)
Comparison Overview
- Semaglutide → GLP-1 only
- Tirzepatide → GLP-1 + GIP
- Retatrutide → GLP-1 + GIP + Glucagon
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FAQ
Is GLP-1 safe?
Generally safe under medical supervision.
Does GLP-1 help weight loss?
Yes, by reducing appetite and calorie intake.
What is the strongest GLP-1 drug?
Retatrutide shows the strongest mechanism in clinical trials.
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