JP Lab Vasoactive Intestinal Peptide (VIP)

Research Grade Peptide | 99.42% Purity | Independently Tested | Endotoxin-Safe Certified

• Purity: 99.42%
• Cost Per Milligram: $4.95 – $7.50
• Endotoxin-Safe Certified: Yes
• Independently Tested: Yes
• Manufacturer ID: SH07
• Batch ID: VP20250511

What Is Vasoactive Intestinal Peptide (VIP)?

Vasoactive Intestinal Peptide (VIP) is a naturally occurring neuropeptide widely distributed throughout the nervous system, gastrointestinal tract, and immune system. VIP has been extensively studied for its involvement in cellular communication, receptor signaling, immune regulation, circadian rhythm control, and gastrointestinal function.

Researchers continue to investigate VIP due to its broad biological activity and its role in maintaining physiological homeostasis across multiple organ systems.

Research Highlights

ACE2 and TMPRSS2 Receptor Expression Research

Recent laboratory studies have demonstrated that VIP influences the expression and regulation of cellular receptors involved in host-pathogen interactions. Researchers observed reduced expression of ACE2 and TMPRSS2 proteins alongside increased receptor shedding mechanisms mediated through ADAM10 signaling pathways.

These findings highlight VIP's importance in receptor biology and cellular surface protein regulation.

Circadian Rhythm and Neuronal Signaling

Research conducted using suprachiasmatic nucleus (SCN) neuronal models demonstrated that VIP can produce sustained changes in neuronal firing activity through VIPR2 receptor signaling pathways.

The study identified downstream involvement of cAMP signaling, PER1 clock proteins, and potassium channel regulation, supporting VIP's established role in circadian rhythm and biological clock research.

Intestinal Epithelial Regeneration Research

Studies utilizing intestinal organoid models have shown that VIP promotes secretory cell differentiation and supports epithelial regeneration pathways. Researchers observed modulation of intestinal progenitor cell activity and enhancement of cellular recovery mechanisms following experimental stress conditions.

These findings contribute to ongoing research investigating VIP's role in gastrointestinal homeostasis and epithelial biology.

Key Research Areas

• Neuropeptide Signaling
• VIP Receptor Biology
• Immune System Research
• Cellular Communication Pathways
• Circadian Rhythm Research
• Neuronal Activity Studies
• Gastrointestinal Function Research
• Epithelial Regeneration Research
• Inflammatory Signaling Pathways
• Homeostasis and Cellular Regulation

Why Choose JP Lab VIP?

• 99.42% Verified Purity
• Independent Third-Party Testing
• USP <85> Endotoxin-Safe Certification
• Research-Grade Manufacturing Standards
• Batch-Specific Quality Verification
• Comprehensive Analytical Documentation
• Trusted by Researchers Worldwide

Product Specifications

Product Name	Vasoactive Intestinal Peptide (VIP)
Purity	99.42%
Manufacturer ID	SH07
Batch ID	VP20250511
Testing	Independently Verified
Endotoxin Status	USP <85> Certified Endotoxin-Safe

Frequently Asked Questions

What is VIP?

VIP is a naturally occurring neuropeptide studied for its role in cellular signaling, receptor activity, circadian rhythm regulation, gastrointestinal physiology, and immune system communication.

What purity level does JP Lab provide?

JP Lab VIP is independently tested and verified at 99.42% purity.

Is every batch tested?

Yes. Each batch undergoes independent analytical verification and quality control testing before release.

Research Use Only

This product is intended strictly for laboratory research purposes. It is not intended for human consumption, veterinary use, diagnosis, treatment, cure, or prevention of any disease. All information presented on this page is provided solely for educational and scientific reference purposes.